MRPL28/YDR462W Summary Help

Standard Name MRPL28 1
Systematic Name YDR462W
Feature Type ORF, Verified
Description Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress (1, 2, 3)
Name Description Mitochondrial Ribosomal Protein, Large subunit 1
Gene Product Alias YmL28 1
Chromosomal Location
ChrIV:1386073 to 1386516 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MRPL28 GO evidence and references
  View Computational GO annotations for MRPL28
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Large-scale survey
null
Resources
53 total interaction(s) for 37 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 44
  • Affinity Capture-RNA: 3

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 147
Molecular Weight (Da) 17,342
Isoelectric Point (pI) 11.27
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1386073 to 1386516 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..444 1386073..1386516 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002870
References cited on this page View Complete Literature Guide for MRPL28
1) Kitakawa M, et al.  (1997) Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Eur J Biochem 245(2):449-56
2) Graack HR and Wittmann-Liebold B  (1998) Mitochondrial ribosomal proteins (MRPs) of yeast. Biochem J 329 ( Pt 3)():433-48
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76