YHP1/YDR451C Summary Help

Standard Name YHP1 1
Systematic Name YDR451C
Feature Type ORF, Verified
Description Homeobox transcriptional repressor; binds Mcm1p and early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval; YHP1 has a paralog, YOX1, that arose from the whole genome duplication (2, 3, 4)
Name Description Yeast Homeo-Protein 1
Chromosomal Location
ChrIV:1362181 to 1361120 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YHP1 GO evidence and references
  View Computational GO annotations for YHP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Targets 16 genes
Regulators 21 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
overexpression
Resources
57 total interaction(s) for 55 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 2
  • Biochemical Activity: 12
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Growth Defect: 5
  • Negative Genetic: 22
  • Positive Genetic: 9
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 353
Molecular Weight (Da) 39,598
Isoelectric Point (pI) 10.75
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1362181 to 1361120 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1062 1362181..1361120 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002859
References cited on this page View Complete Literature Guide for YHP1
1) Kunoh T, et al.  (2000) YHP1 encodes a new homeoprotein that binds to the IME1 promoter in Saccharomyces cerevisiae. Yeast 16(5):439-49
2) Pramila T, et al.  (2002) Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle. Genes Dev 16(23):3034-45
3) Breeden LL  (2003) Periodic transcription: a cycle within a cycle. Curr Biol 13(1):R31-8
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61