GPI19/YDR437W Summary Help

Standard Name GPI19 1
Systematic Name YDR437W
Feature Type ORF, Verified
Description Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI; N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI) is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis; shares similarity with mammalian PIG-P (1, 2)
Name Description Glycosyl PhosphatidylInositol anchor biosynthesis 1
Chromosomal Location
ChrIV:1337352 to 1337774 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All GPI19 GO evidence and references
  View Computational GO annotations for GPI19
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Classical genetics
null
Large-scale survey
conditional
null
overexpression
reduction of function
repressible
Resources
10 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 1
  • Co-purification: 1

Genetic Interactions
  • Negative Genetic: 3
  • Positive Genetic: 4
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 140
Molecular Weight (Da) 16,089
Isoelectric Point (pI) 4
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1337352 to 1337774 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..423 1337352..1337774 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002845
References cited on this page View Complete Literature Guide for GPI19
1) Newman HA, et al.  (2005) Gpi19, the Saccharomyces cerevisiae homologue of mammalian PIG-P, is a subunit of the initial enzyme for glycosylphosphatidylinositol anchor biosynthesis. Eukaryot Cell 4(11):1801-7
2) Watanabe R, et al.  (2000) Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2. EMBO J 19(16):4402-11