RPN9/YDR427W Summary

RPN9 BASIC INFORMATION

Standard Name	RPN9 1
Systematic Name	YDR427W
Feature Type	ORF, Verified
Description	Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects (2, 3)
Name Description	Regulatory Particle Non-ATPase 1

GO Annotations	All RPN9 GO evidence and references
	View Computational GO annotations for RPN9
Molecular Function
Manually curated	structural molecule activity (IMP)
Biological Process
Manually curated	proteasome assembly (IMP) ubiquitin-dependent protein catabolic process (IMP)
Cellular Component
Manually curated	proteasome regulatory particle, lid subcomplex (IDA, IPI) proteasome storage granule (IDA)

Mutant Phenotype	All RPN9 Phenotype details and references
Large-scale survey
null	inviable vegetative growth: normal

Interactions	RPN9 All interactions details and references
	156 total interaction(s) for 51 unique genes/features.
Physical Interactions	Affinity Capture-MS: 122 Affinity Capture-RNA: 1 Affinity Capture-Western: 16 Co-purification: 3 PCA: 3 Two-hybrid: 8
Genetic Interactions	Dosage Lethality: 1 Synthetic Rescue: 2

Sequence Information

ChrIV:1322198 to 1323379 | |

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1182	1322198..1323379	2008-06-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002835

RPN9 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for RPN9

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RPN9]

1)	Finley D, et al. (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5
2)	Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62
3)	Takeuchi J and Toh-e A (2001) Genetic dissection of the yeast 26S proteasome: cell cycle defects caused by the Deltarpn9 mutation. Biochimie 83(3-4):333-40

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