SXM1/YDR395W Summary Help

SXM1 BASIC INFORMATION

Standard Name SXM1 1
Systematic Name YDR395W
Alias KAP108
Feature Type ORF, Verified
Description Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1 (1, 2, 3, 4)
Name Description Suppressor of mRNA eXport Mutant 1
GO Annotations All SXM1 GO evidence and references
    View Computational GO annotations for SXM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SXM1 Phenotype details and references
Classical genetics
dominant negative
null
Large-scale survey
null
Interactions SXM1 All interactions details and references
53 total interaction(s) for 43 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-Western: 4
  • Reconstituted Complex: 3
  • Two-hybrid: 3
Genetic Interactions
  • Phenotypic Enhancement: 10
  • Phenotypic Suppression: 11
  • Synthetic Growth Defect: 2
Sequence Information
ChrIV:1263317 to 1266151 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2835 1263317..1266151 2008-06-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002803

SXM1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SXM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SXM1]

1) Seedorf M and Silver PA  (1997) Importin/karyopherin protein family members required for mRNA export from the nucleus. Proc Natl Acad Sci U S A 94(16):8590-5
2) Seedorf M, et al.  (1999) Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase. Mol Cell Biol 19(2):1547-57
3) Rosenblum JS, et al.  (1997) A nuclear import pathway for a protein involved in tRNA maturation. J Cell Biol 139(7):1655-61
4) Sydorskyy Y, et al.  (2003) Intersection of the Kap123p-mediated nuclear import and ribosome export pathways. Mol Cell Biol 23(6):2042-54