Standard Name	SHE9 1
Systematic Name	YDR393W
Alias	MDM33
Feature Type	ORF, Verified
Description	Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex (2)
Name Description	Sensitivity to High Expression 1

Chromosomal Location	ChrIV:1259901 to 1261271 | ORF Map | GBrowse

	View Computational GO annotations for SHE9
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	inner mitochondrial membrane organization (IGI, IMP) mitochondrion organization (IMP)
Cellular Component
Manually curated	mitochondrial inner membrane (IDA)

Large-scale survey
null	budding index: increased chitin deposition: normal competitive fitness: decreased dessication resistance: decreased haploinsufficient heat sensitivity: increased mitochondrial morphology: abnormal resistance to ethanol: decreased resistance to sulfometuron methyl: decreased resistance to Calcofluor White: normal resistance to arsenite(3-): decreased respiratory growth: decreased rate sporulation: decreased sporulation efficiency: decreased stress resistance: increased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	103 total interaction(s) for 91 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Reconstituted Complex: 1 Two-hybrid: 40
Genetic Interactions	Negative Genetic: 46 Positive Genetic: 10 Synthetic Growth Defect: 2 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1259901 to 1261271 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1371 1259901..1261271 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002801