RVS167/YDR388W Summary Help

RVS167 BASIC INFORMATION

Standard Name RVS167 1, 2
Systematic Name YDR388W
Feature Type ORF, Verified
Description Actin-associated protein, interacts with Rvs161p to regulate actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin (1, 3, 4, 5)
Name Description Reduced Viability on Starvation 1
GO Annotations All RVS167 GO evidence and references
    View Computational GO annotations for RVS167
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All RVS167 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions RVS167 All interactions details and references
448 total interaction(s) for 261 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 119
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 10
  • Biochemical Activity: 7
  • Far Western: 3
  • PCA: 4
  • Protein-peptide: 11
  • Reconstituted Complex: 7
  • Two-hybrid: 132
Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 7
  • Phenotypic Suppression: 3
  • Synthetic Growth Defect: 17
  • Synthetic Lethality: 125
Sequence Information
ChrIV:1250179 to 1251627 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1449 1250179..1251627 2008-06-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002796

RVS167 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for RVS167

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RVS167]

1) Bauer F, et al.  (1993) Alteration of a yeast SH3 protein leads to conditional viability with defects in cytoskeletal and budding patterns. Mol Cell Biol 13(8):5070-84
2) Crouzet, M., et al.  (1992) ; Personal Communication, Mortimer Map Edition 11
3) Balguerie A, et al.  (1999) Rvs167p, the budding yeast homolog of amphiphysin, colocalizes with actin patches. J Cell Sci 112 ( Pt 15)():2529-37
4) Lila T and Drubin DG  (1997) Evidence for physical and functional interactions among two Saccharomyces cerevisiae SH3 domain proteins, an adenylyl cyclase-associated protein and the actin cytoskeleton. Mol Biol Cell 8(2):367-85
5) Lombardi R and Riezman H  (2001) Rvs161p and Rvs167p, the two yeast amphiphysin homologs, function together in vivo. J Biol Chem 276(8):6016-22