Standard Name	ARO10 1
Systematic Name	YDR380W
Feature Type	ORF, Verified
Description	Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway (2)
Name Description	AROmatic amino acid requiring 1

Chromosomal Location	ChrIV:1234218 to 1236125 | ORF Map | GBrowse

	View Computational GO annotations for ARO10
Molecular Function
Manually curated	carboxy-lyase activity (IMP, ISS) phenylpyruvate decarboxylase activity (IDA) pyruvate decarboxylase activity (ISS)
Biological Process
Manually curated	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway (IGI) branched-chain amino acid catabolic process to alcohol via Ehrlich pathway (IGI) L-phenylalanine catabolic process (IDA, IGI) leucine catabolic process (IGI, IMP) methionine catabolic process to 3-methylthiopropanol (IMP) tryptophan catabolic process (IGI)
Cellular Component
High-throughput	cytoplasm (IDA)

Pathways	isoleucine degradation leucine degradation phenylalanine degradation tryptophan degradation

Large-scale survey
null	competitive fitness: increased haploinsufficient resistance to neomycin: decreased resistance to amitrole: decreased resistance to cycloheximide: decreased starvation resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	11 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 PCA: 2
Genetic Interactions	Negative Genetic: 2 Positive Genetic: 2 Synthetic Growth Defect: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1234218 to 1236125 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1908 1234218..1236125 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002788