ARO10/YDR380W Summary Help

Standard Name ARO10 1
Systematic Name YDR380W
Feature Type ORF, Verified
Description Phenylpyruvate decarboxylase; catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway; involved in protein N-terminal Met and Ala catabolism (2, 3)
Name Description AROmatic amino acid requiring 1
Chromosomal Location
ChrIV:1234218 to 1236125 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ARO10 GO evidence and references
  View Computational GO annotations for ARO10
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 15 genes
Resources
Pathways
Large-scale survey
null
Resources
13 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1
  • PCA: 2

Genetic Interactions
  • Negative Genetic: 2
  • Positive Genetic: 2
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 635
Molecular Weight (Da) 71,384
Isoelectric Point (pI) 6.51
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1234218 to 1236125 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1908 1234218..1236125 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002788
References cited on this page View Complete Literature Guide for ARO10
1) Iraqui I, et al.  (1999) Transcriptional induction by aromatic amino acids in Saccharomyces cerevisiae. Mol Cell Biol 19(5):3360-71
2) Vuralhan Z, et al.  (2003) Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae. Appl Environ Microbiol 69(8):4534-41
3) Kneen MM, et al.  (2011) Characterization of a thiamin diphosphate-dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae. FEBS J 278(11):1842-53