TRP4/YDR354W Summary Help

Standard Name TRP4
Systematic Name YDR354W
Feature Type ORF, Verified
Description Anthranilate phosphoribosyl transferase; transferase of the tryptophan biosynthetic pathway; catalyzes the phosphoribosylation of anthranilate; subject to the general control system of amino acid biosynthesis (1, 2, 3, 4, 5)
Name Description TRyPtophan requiring
Chromosomal Location
ChrIV:1184747 to 1185889 | ORF Map | GBrowse
Gbrowse
Genetic position: 209 cM
Gene Ontology Annotations All TRP4 GO evidence and references
  View Computational GO annotations for TRP4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 9 genes
Resources
Pathways
Classical genetics
null
unspecified
Large-scale survey
null
unspecified
Resources
53 total interaction(s) for 48 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 3
  • PCA: 2

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 19
  • Positive Genetic: 14
  • Synthetic Growth Defect: 4
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 380
Molecular Weight (Da) 41,374
Isoelectric Point (pI) 6.65
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1184747 to 1185889 | ORF Map | GBrowse
This feature contains embedded feature(s): YDR354C-A
SGD ORF map
Genetic position: 209 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1143 1184747..1185889 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002762
References cited on this page View Complete Literature Guide for TRP4
1) Toyn JH, et al.  (2000) A counterselection for the tryptophan pathway in yeast: 5-fluoroanthranilic acid resistance. Yeast 16(6):553-60
2) Furter R, et al.  (1988) Regulation of the TRP4 gene of Saccharomyces cerevisiae at the transcriptional level and functional analysis of its promotor. Mol Gen Genet 211(1):168-75
3) Furter R, et al.  (1986) The TRP4 gene of Saccharomyces cerevisiae: isolation and structural analysis. Nucleic Acids Res 14(16):6357-73
4) Braus G, et al.  (1989) Interpathway regulation of the TRP4 gene of yeast. EMBO J 8(3):939-45
5) Duvel K, et al.  (2002) Replacement of the yeast TRP4 3' untranslated region by a hammerhead ribozyme results in a stable and efficiently exported mRNA that lacks a poly(A) tail. RNA 8(3):336-44