Standard Name	HXT3
Systematic Name	YDR345C
Feature Type	ORF, Verified
Description	Low affinity glucose transporter of the major facilitator superfamily; expression is induced in low or high glucose conditions; HXT3 has a paralog, HXT5, that arose from the whole genome duplication (1, 2)
Name Description	HeXose Transporter

Chromosomal Location	ChrIV:1164660 to 1162957 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 209.07 cM

	View Computational GO annotations for HXT3
Molecular Function
Manually curated	fructose transmembrane transporter activity (TAS) glucose transmembrane transporter activity (IDA, TAS) mannose transmembrane transporter activity (TAS)
Biological Process
Manually curated	hexose transport (TAS) transmembrane transport (TAS)
Cellular Component
Manually curated	plasma membrane (IDA, ISS)
High-throughput	integral to membrane (ISM)

Classical genetics
null	resistance to quinine: increased
unspecified	resistance to sodium(1+): decreased
Large-scale survey
null	competitive fitness: decreased haploproficient viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	47 total interaction(s) for 37 unique genes/features.
Physical Interactions	Affinity Capture-MS: 9 Affinity Capture-RNA: 3 Co-fractionation: 2 PCA: 1 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 5 Negative Genetic: 8 Phenotypic Enhancement: 6 Phenotypic Suppression: 2 Positive Genetic: 2 Synthetic Growth Defect: 2 Synthetic Lethality: 2 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Mass Spec

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1164660 to 1162957 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 209.07 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1704 1164660..1162957 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000002753