HXT6/YDR343C Summary

HXT6 BASIC INFORMATION

Standard Name	HXT6
Systematic Name	YDR343C
Feature Type	ORF, Verified
Description	High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3 (1, 2, 3)
Name Description	HeXose Transporter

GO Annotations	All HXT6 GO evidence and references
	View Computational GO annotations for HXT6
Molecular Function
Manually curated	fructose transmembrane transporter activity (TAS) glucose transmembrane transporter activity (IDA, TAS) mannose transmembrane transporter activity (TAS)
Biological Process
Manually curated	hexose transport (TAS) transmembrane transport (TAS)
Cellular Component
Manually curated	membrane fraction (IDA) plasma membrane (ISS)
High-throughput	mitochondrion (IDA) plasma membrane enriched fraction (IDA)

Interactions	HXT6 All interactions details and references
	22 total interaction(s) for 22 unique genes/features.
Physical Interactions	Affinity Capture-MS: 11 Affinity Capture-RNA: 1 Co-fractionation: 2 Two-hybrid: 2
Genetic Interactions	Phenotypic Enhancement: 6

Sequence Information

ChrIV:1161315 to 1159603 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1713	1161315..1159603	2008-06-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000002751

HXT6 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for HXT6

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for HXT6]

1)	Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
2)	Reifenberger E, et al. (1997) Kinetic characterization of individual hexose transporters of Saccharomyces cerevisiae and their relation to the triggering mechanisms of glucose repression. Eur J Biochem 245(2):324-33
3)	Liang H and Gaber RF (1996) A novel signal transduction pathway in Saccharomyces cerevisiae defined by Snf3-regulated expression of HXT6. Mol Biol Cell 7(12):1953-66

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