INM2/YDR287W Summary Help

Standard Name INM2 1
Systematic Name YDR287W
Feature Type ORF, Verified
Description Inositol monophosphatase; involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy (2)
Name Description INositol Monophosphatase 1
Chromosomal Location
ChrIV:1035995 to 1036873 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All INM2 GO evidence and references
  View Computational GO annotations for INM2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Pathways
Classical genetics
overexpression
Large-scale survey
null
Resources
22 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2

Genetic Interactions
  • Negative Genetic: 15
  • Positive Genetic: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 292
Molecular Weight (Da) 32,092
Isoelectric Point (pI) 5.49
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1035995 to 1036873 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..879 1035995..1036873 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002695
References cited on this page View Complete Literature Guide for INM2
1) Murray M and Greenberg ML  (2000) Expression of yeast INM1 encoding inositol monophosphatase is regulated by inositol, carbon source and growth stage and is decreased by lithium and valproate. Mol Microbiol 36(3):651-61
2) Lopez F, et al.  (1999) The yeast inositol monophosphatase is a lithium- and sodium-sensitive enzyme encoded by a non-essential gene pair. Mol Microbiol 31(4):1255-64