Standard Name	ZIP1 1
Systematic Name	YDR285W
Feature Type	ORF, Verified
Description	Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate (2, 3, 4, 5)
Name Description	molecular ZIPper 1

Chromosomal Location	ChrIV:1032436 to 1035063 | ORF Map | GBrowse

	View Computational GO annotations for ZIP1
Molecular Function
Manually curated	chromatin binding (TAS) SUMO polymer binding (IPI)
Biological Process
Manually curated	reciprocal meiotic recombination (IMP) synapsis (IGI, IMP)
Cellular Component
Manually curated	transverse filament (IDA)

Classical genetics
null	chromosome/plasmid maintenance: abnormal meiosis: abnormal meiotic recombination: decreased spore germination: decreased sporulation efficiency: decreased
reduction of function	meiosis: abnormal
Large-scale survey
null	competitive fitness: normal resistance to cycloheximide: decreased resistance to neomycin: decreased sporulation: decreased sporulation efficiency: decreased transposable element transposition: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	89 total interaction(s) for 66 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-Western: 1 Biochemical Activity: 2 Reconstituted Complex: 1 Two-hybrid: 42
Genetic Interactions	Dosage Rescue: 5 Negative Genetic: 6 Phenotypic Enhancement: 10 Phenotypic Suppression: 6 Synthetic Growth Defect: 3 Synthetic Rescue: 8
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:1032436 to 1035063 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2628 1032436..1035063 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002693