DPP1/YDR284C Summary Help

Standard Name DPP1 1
Systematic Name YDR284C
Alias ZRG1 2
Feature Type ORF, Verified
Description Diacylglycerol pyrophosphate (DGPP) phosphatase; zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism (1, 2, 3, 4, 5, 6)
Name Description Diacylglycerol Pyrophosphate Phosphatase 1
Chromosomal Location
ChrIV:1031419 to 1030550 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All DPP1 GO evidence and references
  View Computational GO annotations for DPP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
48 total interaction(s) for 45 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Affinity Capture-RNA: 3
  • PCA: 13
  • Two-hybrid: 6

Genetic Interactions
  • Negative Genetic: 7
  • Phenotypic Enhancement: 2
  • Positive Genetic: 5
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 289
Molecular Weight (Da) 33,514
Isoelectric Point (pI) 6.42
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1031419 to 1030550 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..870 1031419..1030550 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002692
References cited on this page View Complete Literature Guide for DPP1
1) Toke DA, et al.  (1998) Isolation and characterization of the Saccharomyces cerevisiae DPP1 gene encoding diacylglycerol pyrophosphate phosphatase. J Biol Chem 273(6):3278-84
2) Yuan DS  (2000) Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging. Genetics 156(1):45-58
3) Toke DA, et al.  (1999) Mutagenesis of the phosphatase sequence motif in diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae. Biochemistry 38(44):14606-13
4) Furneisen JM and Carman GM  (2000) Enzymological properties of the LPP1-encoded lipid phosphatase from Saccharomyces cerevisiae. Biochim Biophys Acta 1484(1):71-82
5) Wu WI, et al.  (1996) Purification and characterization of diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae. J Biol Chem 271(4):1868-76
6) Han GS, et al.  (2001) Regulation of the Saccharomyces cerevisiae DPP1-encoded diacylglycerol pyrophosphate phosphatase by zinc. J Biol Chem 276(13):10126-33