BSC2/YDR275W Summary Help

Standard Name BSC2 1
Systematic Name YDR275W
Feature Type ORF, Verified
Description Protein of unknown function; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; null mutant displays increased translation rate and increased readthrough of premature stop codons; BSC2 has a paralog, IRC23, that arose from the whole genome duplication (1, 2, 3)
Name Description Bypass of Stop Codon 1
Chromosomal Location
ChrIV:1012252 to 1012959 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All BSC2 GO evidence and references
  View Computational GO annotations for BSC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
unspecified
Resources
5 total interaction(s) for 5 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • PCA: 1

Genetic Interactions
  • Negative Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 235
Molecular Weight (Da) 26,581
Isoelectric Point (pI) 5.1
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1012252 to 1012959 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..708 1012252..1012959 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002683
References cited on this page View Complete Literature Guide for BSC2
1) Namy O, et al.  (2003) Identification of stop codon readthrough genes in Saccharomyces cerevisiae. Nucleic Acids Res 31(9):2289-96
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Samanfar B, et al.  (2014) A global investigation of gene deletion strains that affect premature stop codon bypass in yeast, Saccharomyces cerevisiae. Mol Biosyst 10(4):916-24