SEC26/YDR238C Summary Help

Standard Name SEC26 1
Systematic Name YDR238C
Feature Type ORF, Verified
Description Essential beta-coat protein of the COPI coatomer; involved in ER-to-Golgi protein trafficking and maintenance of normal ER morphology; shares 43% sequence identity with mammalian beta-coat protein (beta-COP) (1)
Name Description SECretory
Chromosomal Location
ChrIV:940816 to 937895 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SEC26 GO evidence and references
  View Computational GO annotations for SEC26
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 10 genes
Resources
Classical genetics
null
repressible
Large-scale survey
null
overexpression
reduction of function
repressible
Resources
149 total interaction(s) for 97 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 76
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 3
  • Co-purification: 2
  • PCA: 10
  • Protein-peptide: 2
  • Reconstituted Complex: 4
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 10
  • Negative Genetic: 25
  • Positive Genetic: 4
  • Synthetic Lethality: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 973
Molecular Weight (Da) 109,018
Isoelectric Point (pI) 5.42
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:940816 to 937895 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2922 940816..937895 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002646
References cited on this page View Complete Literature Guide for SEC26
1) Duden R, et al.  (1994) Yeast beta- and beta'-coat proteins (COP). Two coatomer subunits essential for endoplasmic reticulum-to-Golgi protein traffic. J Biol Chem 269(39):24486-95