PRP42/YDR235W Summary

PRP42 BASIC INFORMATION

Standard Name	PRP42
Systematic Name	YDR235W
Alias	MUD16 , SNU65
Feature Type	ORF, Verified
Description	U1 snRNP protein involved in splicing, required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats (1)
Name Description	Pre-mRNA Processing

GO Annotations	All PRP42 GO evidence and references
	View Computational GO annotations for PRP42
Molecular Function
Manually curated	RNA binding (IDA)
Biological Process
Manually curated	nuclear mRNA splicing, via spliceosome (IMP)
Cellular Component
Manually curated	U1 snRNP (IDA) U2-type prespliceosome (IDA)

Mutant Phenotype	All PRP42 Phenotype details and references
Large-scale survey
conditional	heat sensitivity: increased
null	filamentous growth: decreased invasive growth: absent inviable

Interactions	PRP42 All interactions details and references
	65 total interaction(s) for 30 unique genes/features.
Physical Interactions	Affinity Capture-MS: 52 Co-localization: 1 Co-purification: 1
Genetic Interactions	Phenotypic Enhancement: 9 Synthetic Lethality: 2

Sequence Information

ChrIV:933501 to 935135 | |

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1635	933501..935135	2008-06-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002643

PRP42 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PRP42

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PRP42]

1)	Gottschalk A, et al. (1998) A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA 4(4):374-93

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