CCT6/YDR188W Summary Help

Standard Name CCT6
Systematic Name YDR188W
Alias HTR3 , TCP6 , TCP20
Feature Type ORF, Verified
Description Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif (1, 2, 3)
Name Description Chaperonin Containing TCP-1
Chromosomal Location
ChrIV:836421 to 838061 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CCT6 GO evidence and references
  View Computational GO annotations for CCT6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 11 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
conditional
null
overexpression
repressible
Resources
134 total interaction(s) for 114 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 99
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • Biochemical Activity: 3
  • Co-purification: 1
  • PCA: 2
  • Reconstituted Complex: 8

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 16

Resources
Expression Summary
histogram
Resources
Length (a.a.) 546
Molecular Weight (Da) 59,923
Isoelectric Point (pI) 5.65
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:836421 to 838061 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1641 836421..838061 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002596
References cited on this page View Complete Literature Guide for CCT6
1) Stoldt V, et al.  (1996) Review: the Cct eukaryotic chaperonin subunits of Saccharomyces cerevisiae and other yeasts. Yeast 12(6):523-9
2) Kim S, et al.  (1994) Cystosolic chaperonin subunits have a conserved ATPase domain but diverged polypeptide-binding domains. Trends Biochem Sci 19(12):543-8
3) Anaul Kabir M, et al.  (2005) Physiological effects of unassembled chaperonin Cct subunits in the yeast Saccharomyces cerevisiae. Yeast 22(3):219-39