CSN9/YDR179C Summary Help

Standard Name CSN9 1
Systematic Name YDR179C
Feature Type ORF, Verified
Description Subunit of the Cop9 signalosome; Cop9 signalosome is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling (1, 2)
Name Description Cop9 SigNalosome subunit 1
Chromosomal Location
ChrIV:819196 to 818708 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CSN9 GO evidence and references
  View Computational GO annotations for CSN9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
75 total interaction(s) for 42 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 32
  • Affinity Capture-Western: 3
  • Biochemical Activity: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 13

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 18
  • Positive Genetic: 3
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 162
Molecular Weight (Da) 19,476
Isoelectric Point (pI) 4.88
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:819196 to 818708 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..489 819196..818708 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002586
References cited on this page View Complete Literature Guide for CSN9
1) Maytal-Kivity V, et al.  (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21
2) Wee S, et al.  (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15