NGG1/YDR176W Summary Help

NGG1 BASIC INFORMATION

Standard Name NGG1
Systematic Name YDR176W
Alias ADA3 , SWI7
Feature Type ORF, Verified
Description Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex (1, 2, 3, 4)
GO Annotations All NGG1 GO evidence and references
    View Computational GO annotations for NGG1
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
Mutant Phenotype All NGG1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions NGG1 All interactions details and references
240 total interaction(s) for 111 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 75
  • Affinity Capture-Western: 50
  • Co-fractionation: 4
  • Co-purification: 9
  • Reconstituted Complex: 8
  • Two-hybrid: 12
Genetic Interactions
  • Phenotypic Enhancement: 25
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 41
  • Synthetic Lethality: 14
  • Synthetic Rescue: 1
Sequence Information
ChrIV:814450 to 816558 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2109 814450..816558 2008-06-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002583

NGG1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for NGG1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NGG1]

1) Saleh A, et al.  (1997) Identification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2. J Biol Chem 272(9):5571-8
2) Brandl CJ, et al.  (1993) Characterization of NGG1, a novel yeast gene required for glucose repression of GAL4p-regulated transcription. EMBO J 12(13):5255-65
3) Grant PA, et al.  (1998) A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation. Cell 94(1):45-53
4) Pray-Grant MG, et al.  (2002) The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway. Mol Cell Biol 22(24):8774-86