SEC5/YDR166C Summary Help

SEC5 BASIC INFORMATION

Standard Name SEC5 1, 2
Systematic Name YDR166C
Feature Type ORF, Verified
Description Essential 107kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis (3)
Name Description SECretory 4
GO Annotations All SEC5 GO evidence and references
    View Computational GO annotations for SEC5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All SEC5 Phenotype details and references
Classical genetics
conditional
Large-scale survey
null
repressible
Interactions SEC5 All interactions details and references
123 total interaction(s) for 42 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 37
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 7
  • Co-fractionation: 6
  • Co-purification: 1
  • PCA: 2
  • Reconstituted Complex: 9
  • Two-hybrid: 5
Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Dosage Rescue: 13
  • Phenotypic Suppression: 3
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 36
Sequence Information
ChrIV:789219 to 786304 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 95 cM
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2916 789219..786304 2008-06-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002573

SEC5 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for SEC5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SEC5]

1) Novick P, et al.  (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
2) Fields, C. and Schekman, R.  (1985) Personal Communication, Mortimer Map Edition 9
3) TerBush DR, et al.  (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94
4) Novick P and Schekman R  (1979) Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 76(4):1858-62