RPA14/YDR156W Summary

RPA14 BASIC INFORMATION

Standard Name	RPA14 1
Systematic Name	YDR156W
Feature Type	ORF, Verified
Description	RNA polymerase I subunit A14 (1)
Name Description	RNA Polymerase A
Gene Product Alias	A14 2

GO Annotations	All RPA14 GO evidence and references
	View Computational GO annotations for RPA14
Molecular Function
Manually curated	DNA-directed RNA polymerase activity (IDA)
Biological Process
Manually curated	transcription of nuclear rRNA large RNA polymerase I transcript (IGI, IMP)
High-throughput	regulation of cell size (IMP)
Cellular Component
Manually curated	DNA-directed RNA polymerase I complex (IDA)

Mutant Phenotype	All RPA14 Phenotype details and references
Classical genetics
null	5.8S rRNA accumulation: decreased chromosome/plasmid maintenance: abnormal heat sensitivity: increased viable
Large-scale survey
null	competitive fitness: decreased fermentative growth: decreased rate filamentous growth: increased telomere length: increased transposable element transposition: increased viable
overexpression	cell cycle progression in G1 phase: abnormal vegetative growth: decreased

Interactions	RPA14 All interactions details and references
	158 total interaction(s) for 104 unique genes/features.
Physical Interactions	Affinity Capture-MS: 21 Affinity Capture-RNA: 1 Affinity Capture-Western: 4 Co-crystal Structure: 1 Co-purification: 1 Far Western: 1 PCA: 1 Protein-RNA: 1 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 2 Phenotypic Enhancement: 82 Phenotypic Suppression: 27 Synthetic Growth Defect: 8 Synthetic Lethality: 6

Sequence Information

ChrIV:769523 to 769936 | |

Last Update

Coordinates: 2008-06-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..414	769523..769936	2008-06-05	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002563

RPA14 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for RPA14

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RPA14]

1)	Smid A, et al. (1995) The association of three subunits with yeast RNA polymerase is stabilized by A14. J Biol Chem 270(22):13534-40
2)	Riva M, et al. (1982) Natural variation in yeast RNA polymerase A. Formation of a mosaic RNA polymerase A in a meiotic segregant from an interspecific hybrid. J Biol Chem 257(8):4570-7

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