Standard Name	SWF1 1
Systematic Name	YDR126W
Alias	PSL10
Feature Type	ORF, Verified
Description	Palmitoyltransferase that acts on transmembrane proteins, including the SNAREs Snc1p, Syn8p, Tlg1p and likely all SNAREs; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion (1, 2, 3, 4)
Name Description	Spore Wall Formation 1

Chromosomal Location	ChrIV:703234 to 704244 | ORF Map | GBrowse

	View Computational GO annotations for SWF1
Molecular Function
Manually curated	palmitoyltransferase activity (IMP, ISS)
Biological Process
Manually curated	cortical actin cytoskeleton organization (IMP) establishment of cell polarity (IMP) protein palmitoylation (IMP) regulation of exocytosis (IMP) vacuole fusion, non-autophagic (IGI)
High-throughput	ascospore wall assembly (IMP)
Cellular Component
Manually curated	actin cortical patch (IDA) actin filament bundle (IDA) integral to membrane (ISS) nuclear outer membrane-endoplasmic reticulum membrane network (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	actin cytoskeleton morphology: abnormal cell shape: abnormal oxidative stress resistance: decreased BGL2 secretion: decreased resistance to latrunculin A: decreased resistance to Calcofluor White: decreased utilization of carbon source: absent
repressible	palmitoylated protein modification: decreased
Large-scale survey
null	acid pH resistance: decreased polyphosphate accumulation: abnormal competitive fitness: decreased dessication resistance: decreased freeze-thaw resistance: decreased haploinsufficient hyperosmotic stress resistance: decreased resistance to amiodarone: decreased resistance to caffeine: decreased resistance to calcium dichloride: decreased resistance to mefloquine: decreased resistance to sirolimus: decreased resistance to pyrrolidine dithiocarbamate: decreased resistance to ethanol: decreased resistance to wortmannin: decreased resistance to hygromycin B: decreased spore wall formation: absent stress resistance: increased utilization of carbon source: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	241 total interaction(s) for 184 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 PCA: 1
Genetic Interactions	Negative Genetic: 171 Phenotypic Enhancement: 2 Positive Genetic: 11 Synthetic Growth Defect: 31 Synthetic Lethality: 22 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:703234 to 704244 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1011 703234..704244 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002533