VBA4/YDR119W Summary Help

Standard Name VBA4 1
Systematic Name YDR119W
Feature Type ORF, Uncharacterized
Description Protein of unknown function; proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene (1, 2, 3, 4)
Name Description Vacuolar Basic Amino acid transporter 1
Chromosomal Location
ChrIV:688227 to 690533 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All VBA4 GO evidence and references
  View Computational GO annotations for VBA4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 5 genes
Resources
Large-scale survey
null
Resources
20 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • PCA: 8
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 5
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 768
Molecular Weight (Da) 85,682
Isoelectric Point (pI) 8.23
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:688227 to 690533 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2307 688227..690533 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000002526
References cited on this page View Complete Literature Guide for VBA4
1) Shimazu M, et al.  (2005) A family of basic amino acid transporters of the vacuolar membrane from Saccharomyces cerevisiae. J Biol Chem 280(6):4851-7
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4) Tarassov K, et al.  (2008) An in vivo map of the yeast protein interactome. Science 320(5882):1465-70