YDR115W Summary Help

Systematic Name YDR115W
Feature Type ORF, Verified
Description Putative mitochondrial ribosomal protein of the large subunit; similar to E. coli L34 ribosomal protein; required for respiratory growth, as are most mitochondrial ribosomal proteins; protein increases in abundance and relocalizes to the plasma membrane upon DNA replication stress (1, 2, 3)
Chromosomal Location
ChrIV:682175 to 682492 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YDR115W GO evidence and references
  View Computational GO annotations for YDR115W
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
11 total interaction(s) for 10 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 4
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Lethality: 1
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 105
Molecular Weight (Da) 12,030
Isoelectric Point (pI)
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:682175 to 682492 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..318 682175..682492 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002522
References cited on this page View Complete Literature Guide for YDR115W
1) Hughes TR, et al.  (2000) Functional discovery via a compendium of expression profiles. Cell 102(1):109-26
2) Gan X, et al.  (2002) Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Eur J Biochem 269(21):5203-14
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76