RRP1/YDR087C Summary Help

Standard Name RRP1 1
Systematic Name YDR087C
Feature Type ORF, Verified
Description Essential evolutionarily conserved nucleolar protein; necessary for biogenesis of 60S ribosomal subunits and for processing of pre-rRNAs to mature rRNA; associated with several distinct 66S pre-ribosomal particles (2)
Name Description Ribosomal RNA Processing
Chromosomal Location
ChrIV:618306 to 617470 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RRP1 GO evidence and references
  View Computational GO annotations for RRP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Large-scale survey
null
reduction of function
Resources
210 total interaction(s) for 162 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 121
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 3
  • Biochemical Activity: 2
  • Reconstituted Complex: 2
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 67
  • Positive Genetic: 7
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 278
Molecular Weight (Da) 33,202
Isoelectric Point (pI) 5.03
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:618306 to 617470 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..837 618306..617470 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002494
References cited on this page View Complete Literature Guide for RRP1
1) Stanford, D.R. et al.  (1997) Personal Communication
2) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27