TGL2/YDR058C Summary Help

Standard Name TGL2
Systematic Name YDR058C
Feature Type ORF, Verified
Description Triacylglycerol lipase that is localized to the mitochondria; has lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli (1, 2)
Name Description TriacylGlycerol Lipase
Chromosomal Location
ChrIV:568703 to 567723 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TGL2 GO evidence and references
  View Computational GO annotations for TGL2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
62 total interaction(s) for 52 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2

Genetic Interactions
  • Negative Genetic: 55
  • Positive Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 326
Molecular Weight (Da) 37,500
Isoelectric Point (pI) 8.41
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:568703 to 567723 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..981 568703..567723 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002465
References cited on this page View Complete Literature Guide for TGL2
1) Van Heusden GP, et al.  (1998) The Saccharomyces cerevisiae TGL2 gene encodes a protein with lipolytic activity and can complement an Escherichia coli diacylglycerol kinase disruptant. Yeast 14(3):225-32
2) Ham HJ, et al.  (2010) The TGL2 gene of saccharomyces cerevisiae encodes an active acylglycerol lipase located in the mitochondria. J Biol Chem 285(5):3005-13