DET1/YDR051C Summary Help

Standard Name DET1 1
Systematic Name YDR051C
Feature Type ORF, Verified
Description Acid phosphatase; involved in the non-vesicular transport of sterols in both directions between the endoplasmic reticulum and plasma membrane; deletion confers sensitivity to nickel (1, 2, 3)
Name Description Decreased Ergosterol Transport 1
Chromosomal Location
ChrIV:558060 to 557056 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All DET1 GO evidence and references
  View Computational GO annotations for DET1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
Resources
13 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 2
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 334
Molecular Weight (Da) 39,172
Isoelectric Point (pI) 7.34
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:558060 to 557056 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1005 558060..557056 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002458
References cited on this page View Complete Literature Guide for DET1
1) Sullivan DP, et al.  (2009) Tritium suicide selection identifies proteins involved in the uptake and intracellular transport of sterols in Saccharomyces cerevisiae. Eukaryot Cell 8(2):161-9
2) Bishop AL, et al.  (2007) Phenotypic heterogeneity can enhance rare-cell survival in 'stress-sensitive' yeast populations. Mol Microbiol 63(2):507-20
3) Ho CK, et al.  (2009) Identification of nucleases and phosphatases by direct biochemical screen of the Saccharomyces cerevisiae proteome. PLoS One 4(9):e6993