SOK1/YDR006C Summary Help

Standard Name SOK1 1
Systematic Name YDR006C
Feature Type ORF, Verified
Description Protein of unknown function; overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13 (1, 2)
Name Description Suppressor Of Kinase 1
Chromosomal Location
ChrIV:461247 to 458542 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SOK1 GO evidence and references
  View Computational GO annotations for SOK1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
43 total interaction(s) for 40 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-RNA: 2
  • Co-purification: 1

Genetic Interactions
  • Dosage Rescue: 6
  • Negative Genetic: 20
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 901
Molecular Weight (Da) 101,081
Isoelectric Point (pI) 9.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:461247 to 458542 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2706 461247..458542 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002413
References cited on this page View Complete Literature Guide for SOK1
1) Ward MP and Garrett S  (1994) Suppression of a yeast cyclic AMP-dependent protein kinase defect by overexpression of SOK1, a yeast gene exhibiting sequence similarity to a developmentally regulated mouse gene. Mol Cell Biol 14(9):5619-27
2) Reisdorf P, et al.  (1997) The MBR1 gene from Saccharomyces cerevisiae is activated by and required for growth under sub-optimal conditions. Mol Gen Genet 255(4):400-9