ADY3/YDL239C Summary Help

Standard Name ADY3 1
Systematic Name YDL239C
Feature Type ORF, Verified
Description Protein required for spore wall formation; thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p; ADY3 has a paralog, CNM67, that arose from the whole genome duplication (2, 3, 4)
Name Description Accumulation of DYads 1
Chromosomal Location
ChrIV:28775 to 26403 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ADY3 GO evidence and references
  View Computational GO annotations for ADY3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 68 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
80 total interaction(s) for 59 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • Co-localization: 1
  • Two-hybrid: 61

Genetic Interactions
  • Negative Genetic: 5
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 790
Molecular Weight (Da) 91,812
Isoelectric Point (pI) 8.95
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:28775 to 26403 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2373 28775..26403 1996-07-31 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002398
References cited on this page View Complete Literature Guide for ADY3
1) Rabitsch KP, et al.  (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9
2) Nickas ME and Neiman AM  (2002) Ady3p links spindle pole body function to spore wall synthesis in Saccharomyces cerevisiae. Genetics 160(4):1439-50
3) Ubersax JA, et al.  (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61