NOP6/YDL213C Summary

NOP6 BASIC INFORMATION

Standard Name	NOP6 1
Systematic Name	YDL213C
Feature Type	ORF, Verified
Description	Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes (2, 3)
Name Description	NucleOlar Protein 1

GO Annotations	All NOP6 GO evidence and references
	View Computational GO annotations for NOP6
Molecular Function
Manually curated	RNA binding (ISS)
Biological Process
Manually curated	ribosomal small subunit biogenesis (IGI)
Cellular Component
Manually curated	nucleolus (IDA)
High-throughput	nucleolus (IDA)

Mutant Phenotype	All NOP6 Phenotype details and references
Classical genetics
null	resistance to brefeldin A: decreased
Large-scale survey
null	glycogen accumulation: increased viable

Interactions	NOP6 All interactions details and references
	108 total interaction(s) for 92 unique genes/features.
Physical Interactions	Affinity Capture-MS: 81 PCA: 4 Two-hybrid: 1
Genetic Interactions	Phenotypic Enhancement: 13 Phenotypic Suppression: 6 Synthetic Growth Defect: 2 Synthetic Rescue: 1

Sequence Information

ChrIV:77967 to 77290 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..678	77967..77290	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002372

NOP6 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for NOP6

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NOP6]

1)	Samanta MP and Liang S (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83
2)	Garay-Arroyo A, et al. (2000) Highly hydrophilic proteins in prokaryotes and eukaryotes are common during conditions of water deficit. J Biol Chem 275(8):5668-74
3)	Buchhaupt M, et al. (2007) Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein. FEMS Yeast Res 7(6):771-81

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