GLE1/YDL207W Summary Help

GLE1 BASIC INFORMATION

Standard Name GLE1 1, 2
Systematic Name YDL207W
Alias RSS1 3 , BRR3 4
Feature Type ORF, Verified
Description Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component of Nup82p nuclear pore subcomplex; contains a nuclear export signal (1, 3, 5)
Name Description GLFG (glycine-leucine-phenylalanine-glycine) LEthal 2
GO Annotations All GLE1 GO evidence and references
    View Computational GO annotations for GLE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All GLE1 Phenotype details and references
Classical genetics
conditional
Large-scale survey
null
overexpression
Interactions GLE1 All interactions details and references
59 total interaction(s) for 28 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-Western: 5
  • Biochemical Activity: 2
  • Co-purification: 1
  • FRET: 1
  • PCA: 1
  • Reconstituted Complex: 9
  • Two-hybrid: 14
Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Dosage Rescue: 5
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 10
  • Synthetic Rescue: 1
Sequence Information
ChrIV:88249 to 89865 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1617 88249..89865 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002366

GLE1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for GLE1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GLE1]

1) Murphy R and Wente SR  (1996) An RNA-export mediator with an essential nuclear export signal. Nature 383(6598):357-60
2) Murphy R, et al.  (1996) GLE2, a Saccharomyces cerevisiae homologue of the Schizosaccharomyces pombe export factor RAE1, is required for nuclear pore complex structure and function. Mol Biol Cell 7(12):1921-37
3) Del Priore V, et al.  (1996) The product of the Saccharomyces cerevisiae RSS1 gene, identified as a high-copy suppressor of the rat7-1 temperature-sensitive allele of the RAT7/NUP159 nucleoporin, is required for efficient mRNA export. Mol Biol Cell 7(10):1601-21
4) Noble SM and Guthrie C  (1996) Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations. Genetics 143(1):67-80
5) Hurwitz ME, et al.  (1998) Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex. Proc Natl Acad Sci U S A 95(19):11241-5