Standard Name	UGA3 1, 2
Systematic Name	YDL170W
Feature Type	ORF, Verified
Description	Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus (3, 4, 5)
Name Description	Utilization of GAba 2

Chromosomal Location	ChrIV:156318 to 157904 | ORF Map | GBrowse

	View Computational GO annotations for UGA3
Molecular Function
Manually curated	RNA polymerase II core promoter proximal region sequence-specific DNA binding (IDA) RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (IDA) sequence-specific DNA binding transcription factor recruiting transcription factor activity (IDA, IGI)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	gamma-aminobutyric acid catabolic process (IMP) nitrogen catabolite activation of transcription from RNA polymerase II promoter (IMP) nitrogen utilization (IMP)
Cellular Component
Manually curated	nucleus (IDA)

Binding motifs	Predicted UGA3 Binding Site Locations
	CCGCCGGCGG 5 [Search intergenic regions for CCGCCGGCGG] TSCCGCSV 6 [Search intergenic regions for TSCCGCSV]
Regulatory modules	predicted: stressResponse (523, 481)
Resources	ScerTF | YEASTRACT | YeTFaSCo

Classical genetics
null	replicative lifespan: increased vegetative growth: decreased rate
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: decreased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to sorbate: increased resistance to nickel sulfate: decreased resistance to amiodarone: decreased vacuolar morphology: abnormal viable
overexpression	filamentous growth: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	22 total interaction(s) for 22 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 2 Co-localization: 1
Genetic Interactions	Negative Genetic: 11 Phenotypic Suppression: 1 Synthetic Growth Defect: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:156318 to 157904 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1587 156318..157904 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002329