ENT1/YDL161W Summary

ENT1 BASIC INFORMATION

Standard Name	ENT1
Systematic Name	YDL161W
Feature Type	ORF, Verified
Description	Epsin-like protein involved in endocytosis and actin patch assembly and functionally redundant with Ent2p; binds clathrin via a clathrin-binding domain motif at C-terminus (1)
Name Description	Epsin N-Terminal homology 1

GO Annotations	All ENT1 GO evidence and references
	View Computational GO annotations for ENT1
Molecular Function
Manually curated	clathrin binding (TAS)
Biological Process
Manually curated	actin cortical patch assembly (IMP) actin filament organization (IMP) endocytosis (IMP)
Cellular Component
Manually curated	actin cortical patch (TAS)
High-throughput	mating projection tip (IDA)

Mutant Phenotype	All ENT1 Phenotype details and references
Large-scale survey
null	viable
overexpression	vegetative growth: decreased

Interactions	ENT1 All interactions details and references
	28 total interaction(s) for 17 unique genes/features.
Physical Interactions	Affinity Capture-Western: 4 Co-localization: 1 Reconstituted Complex: 2 Two-hybrid: 10
Genetic Interactions	Dosage Rescue: 3 Phenotypic Enhancement: 1 Phenotypic Suppression: 2 Synthetic Growth Defect: 3 Synthetic Lethality: 2

Sequence Information

ChrIV:167715 to 169079 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1365	167715..169079	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002320

ENT1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for ENT1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ENT1]

1)	Wendland B, et al. (1999) Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J 18(16):4383-93

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