LUC7/YDL087C Summary Help

LUC7 BASIC INFORMATION

Standard Name LUC7 1
Systematic Name YDL087C
Alias EXM2 , EPE1
Feature Type ORF, Verified
Description Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA (2, 3)
Name Description Lethal Unless Cap-binding complex is produced 1
GO Annotations All LUC7 GO evidence and references
    View Computational GO annotations for LUC7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All LUC7 Phenotype details and references
Large-scale survey
null
Interactions LUC7 All interactions details and references
98 total interaction(s) for 35 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 87
  • Affinity Capture-Western: 2
  • Co-purification: 1
  • Two-hybrid: 4
Genetic Interactions
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Synthetic Lethality: 2
Sequence Information
ChrIV:300999 to 300214 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..786 300999..300214 2004-02-11 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002245

LUC7 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for LUC7

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for LUC7]

1) Fortes P, et al.  (1999) Genetic and physical interactions involving the yeast nuclear cap-binding complex. Mol Cell Biol 19(10):6543-53
2) Fortes P, et al.  (1999) Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition. Genes Dev 13(18):2425-38
3) Puig O, et al.  (2007) The U1 snRNP-associated factor Luc7p affects 5' splice site selection in yeast and human. Nucleic Acids Res 35(17):5874-85