Standard Name	UBC9
Systematic Name	YDL064W
Feature Type	ORF, Verified
Description	SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC) (1, 2, 3)
Name Description	UBiquitin-Conjugating

Chromosomal Location	ChrIV:337487 to 338070 | ORF Map | GBrowse

	View Computational GO annotations for UBC9
Molecular Function
Manually curated	SUMO ligase activity (IDA, IMP)
Biological Process
Manually curated	G2/M transition of mitotic cell cycle (TAS) mitotic spindle elongation (IMP) protein sumoylation (IDA, IMP, IPI)
Cellular Component
Manually curated	condensed nuclear chromosome (IDA) nucleus (IDA)

Classical genetics
activation	cellular morphology: abnormal
conditional	Matalpha1p accumulation: increased Rpo21p modification: absent resistance to doxorubicin: increased
repressible	chromosome/plasmid maintenance: decreased
Large-scale survey
conditional	chromosome/plasmid maintenance: abnormal
null	inviable
repressible	chromosome/plasmid maintenance: decreased
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	104 total interaction(s) for 57 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-RNA: 3 Affinity Capture-Western: 6 Biochemical Activity: 8 Co-crystal Structure: 2 PCA: 2 Reconstituted Complex: 12 Two-hybrid: 37
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 1 Phenotypic Enhancement: 2 Synthetic Growth Defect: 7 Synthetic Lethality: 15 Synthetic Rescue: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:337487 to 338070 | ORF Map | GBrowse
Last Update	Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..38 337487..337524 2004-02-11 1996-07-31 Intron 39..148 337525..337634 2004-02-11 1996-07-31 CDS 149..584 337635..338070 2004-02-11 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (39 - 148)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002222