SLC1/YDL052C Summary Help

Standard Name SLC1 1
Systematic Name YDL052C
Feature Type ORF, Verified
Description 1-acyl-sn-glycerol-3-phosphate acyltransferase; catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes (2, 3)
Name Description SphingoLipid Compensation 1
Chromosomal Location
ChrIV:363583 to 362672 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SLC1 GO evidence and references
  View Computational GO annotations for SLC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 6 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
83 total interaction(s) for 59 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 16
  • Affinity Capture-RNA: 3
  • Co-fractionation: 1
  • Co-purification: 1
  • PCA: 9

Genetic Interactions
  • Negative Genetic: 27
  • Positive Genetic: 12
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 5
  • Synthetic Rescue: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 303
Molecular Weight (Da) 33,887
Isoelectric Point (pI) 10.41
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:363583 to 362672 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..912 363583..362672 2004-02-11 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002210
References cited on this page View Complete Literature Guide for SLC1
1) Nagiec MM, et al.  (1993) A suppressor gene that enables Saccharomyces cerevisiae to grow without making sphingolipids encodes a protein that resembles an Escherichia coli fatty acyltransferase. J Biol Chem 268(29):22156-63
2) Athenstaedt K and Daum G  (1997) Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiae. J Bacteriol 179(24):7611-6
3) Athenstaedt K and Daum G  (1999) Phosphatidic acid, a key intermediate in lipid metabolism. Eur J Biochem 266(1):1-16