KNH1/YDL049C Summary

KNH1 BASIC INFORMATION

Standard Name	KNH1 1
Systematic Name	YDL049C
Feature Type	ORF, Verified
Description	Protein with similarity to Kre9p, which is involved in cell wall beta 1,6-glucan synthesis; overproduction suppresses growth defects of a kre9 null mutant; required for propionic acid resistance (1, 2)
Name Description	Kre9(Nine) Homolog 1

GO Annotations	All KNH1 GO evidence and references
	View Computational GO annotations for KNH1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	1,6-beta-glucan biosynthetic process (IGI, IMP)
Cellular Component
Manually curated	extracellular region (IDA) fungal-type cell wall (NAS)

Mutant Phenotype	All KNH1 Phenotype details and references
Classical genetics
null	acid pH resistance: decreased
Large-scale survey
null	acid pH resistance: decreased viable

Interactions	KNH1 All interactions details and references
	40 total interaction(s) for 37 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1
Genetic Interactions	Dosage Rescue: 1 Synthetic Lethality: 38

Sequence Information

ChrIV:365874 to 365068 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-02-11 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..807	365874..365068	2004-02-11	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002207

KNH1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for KNH1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for KNH1]

1)	Dijkgraaf GJ, et al. (1996) The KNH1 gene of Saccharomyces cerevisiae is a functional homolog of KRE9. Yeast 12(7):683-92
2)	Mira NP, et al. (2009) The RIM101 pathway has a role in Saccharomyces cerevisiae adaptive response and resistance to propionic acid and other weak acids. FEMS Yeast Res 9(2):202-16

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