PRP11/YDL043C Summary

PRP11 BASIC INFORMATION

Standard Name	PRP11
Systematic Name	YDL043C
Alias	RNA11
Feature Type	ORF, Verified
Description	Subunit of the SF3a splicing factor complex, required for spliceosome assembly (1)
Name Description	Pre-mRNA Processing 2

GO Annotations	All PRP11 GO evidence and references
	View Computational GO annotations for PRP11
Molecular Function
Manually curated	RNA binding (IDA)
Biological Process
Manually curated	spliceosome assembly (IDA)
Cellular Component
Manually curated	colocalizes_with U2 snRNP (TAS) U2 snRNP (TAS) U2-type prespliceosome (IDA)

Mutant Phenotype	All PRP11 Phenotype details and references
Classical genetics
conditional	heat sensitivity: increased
Large-scale survey
null	competitive fitness: decreased haploinsufficient inviable

Interactions	PRP11 All interactions details and references
	138 total interaction(s) for 99 unique genes/features.
Physical Interactions	Affinity Capture-MS: 64 Biochemical Activity: 1 Co-purification: 1 PCA: 1 Reconstituted Complex: 6 Two-hybrid: 25
Genetic Interactions	Dosage Rescue: 1 Phenotypic Enhancement: 20 Phenotypic Suppression: 14 Synthetic Lethality: 4 Synthetic Rescue: 1

Sequence Information

ChrIV:376477 to 375677 | |

Note: this feature is encoded on the Crick strand.

Genetic position: -17.13 cM

Last Update

Coordinates: 2004-02-11 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..801	376477..375677	2004-02-11	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002201

PRP11 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PRP11

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PRP11]

1)	Hodges PE and Beggs JD (1994) RNA splicing. U2 fulfils a commitment. Curr Biol 4(3):264-7
2)	Vijayraghavan U, et al. (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16

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