PRP11/YDL043C Summary Help

Standard Name PRP11 1
Systematic Name YDL043C
Alias RNA11 2
Feature Type ORF, Verified
Description Subunit of the SF3a splicing factor complex; required for spliceosome assembly (3)
Name Description Pre-mRNA Processing 1
Chromosomal Location
ChrIV:376480 to 375680 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -17.13 cM
Gene Ontology Annotations All PRP11 GO evidence and references
  View Computational GO annotations for PRP11
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
reduction of function
Resources
144 total interaction(s) for 101 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 68
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Co-purification: 1
  • PCA: 1
  • Reconstituted Complex: 6
  • Two-hybrid: 25

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 20
  • Positive Genetic: 14
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 2
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 266
Molecular Weight (Da) 29,921
Isoelectric Point (pI) 8.18
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:376480 to 375680 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -17.13 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..801 376480..375680 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002201
References cited on this page View Complete Literature Guide for PRP11
1) Vijayraghavan U, et al.  (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16
2) Hartwell LH, et al.  (1970) Identification of ten genes that control ribosome formation in yeast. Mol Gen Genet 109(1):42-56
3) Hodges PE and Beggs JD  (1994) RNA splicing. U2 fulfils a commitment. Curr Biol 4(3):264-7