Standard Name	PRP9
Systematic Name	YDL030W
Feature Type	ORF, Verified
Description	Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex (1, 2)
Name Description	Pre-mRNA Processing 3

Chromosomal Location	ChrIV:397537 to 399129 | ORF Map | GBrowse

	View Computational GO annotations for PRP9
Molecular Function
Manually curated	RNA binding (IDA)
Biological Process
Manually curated	mRNA splicing, via spliceosome (IDA)
Cellular Component
Manually curated	U2 snRNP (TAS) U2-type prespliceosome (IDA)

Classical genetics
conditional	heat sensitivity: increased
null	inviable
Large-scale survey
null	inviable
reduction of function	competitive fitness: normal
repressible	cytokinesis: abnormal
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	116 total interaction(s) for 76 unique genes/features.
Physical Interactions	Affinity Capture-MS: 70 Affinity Capture-Western: 1 Co-purification: 1 Reconstituted Complex: 4 Two-hybrid: 27
Genetic Interactions	Negative Genetic: 5 Synthetic Growth Defect: 1 Synthetic Lethality: 6 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:397537 to 399129 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1593 397537..399129 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002188