| Standard Name | PMP2 1 |
|---|---|
| Systematic Name | YEL017C-A |
| Feature Type | ORF, Verified |
| Description | Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication (1, 2, 3, 4) |
| Name Description | Plasma Membrane Proteolipid 1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All PMP2 GO evidence and references
| View Computational GO annotations for PMP2 | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All PMP2 Phenotype evidence and references
| Large-scale survey | |
|---|---|
| null | |
| Resources |
interactions All PMP2 Interaction evidence and references
| 46 total interaction(s) for 43 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All PMP2 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 1996-07-31 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
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| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000002103 |
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References cited on this page View Complete Literature Guide for PMP2
| 1) | Navarre C, et al. (1994) Two distinct genes encode small isoproteolipids affecting plasma membrane H(+)-ATPase activity of Saccharomyces cerevisiae. J Biol Chem 269(33):21262-8 |
| 2) | Navarre C and Goffeau A (1998) The plasma membrane H(+)-ATPase of Saccharomyces cerevisiae is regulated by two small 38-residue isoproteolipids. Folia Microbiol (Praha) 43(2):206-8 |
| 3) | Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 |
| 4) | Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76 |




