MEI4/YER044C-A Summary Help

Standard Name MEI4 1
Systematic Name YER044C-A
Feature Type ORF, Verified
Description Meiosis-specific protein involved in forming DSBs; involved in double-strand break (DSBs) formation during meiotic recombination; required for chromosome synapsis and production of viable spores (1, 2, 3)
Name Description MEIosis-specific 1, 2
Chromosomal Location
ChrV:239774 to 238460 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 41 cM
Gene Ontology Annotations All MEI4 GO evidence and references
  View Computational GO annotations for MEI4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
reduction of function
Large-scale survey
null
Resources
18 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 2
  • Two-hybrid: 8

Genetic Interactions
  • Negative Genetic: 5
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 408
Molecular Weight (Da) 48,214
Isoelectric Point (pI) 10.38
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:239774 to 238460 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 41 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..63 239774..239712 2011-02-03 1996-07-31
Intron 64..151 239711..239624 2011-02-03 1996-07-31
CDS 152..1315 239623..238460 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001954
References cited on this page View Complete Literature Guide for MEI4
1) Menees TM and Roeder GS  (1989) MEI4, a yeast gene required for meiotic recombination. Genetics 123(4):675-82
2) Menees TM, et al.  (1992) MEI4, a meiosis-specific yeast gene required for chromosome synapsis. Mol Cell Biol 12(3):1340-51
3) Jiao K, et al.  (1999) Coordination of the initiation of recombination and the reductional division in meiosis in Saccharomyces cerevisiae. Genetics 152(1):117-28