IRC7/YFR055W Summary Help

IRC7 BASIC INFORMATION

Standard Name IRC7 1
Systematic Name YFR055W
Feature Type ORF, Uncharacterized
Description Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner (1, 2, 3, 4)
Name Description Increased Recombination Centers 1
GO Annotations All IRC7 GO evidence and references
    View Computational GO annotations for IRC7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All IRC7 Phenotype details and references
Large-scale survey
null
Interactions IRC7 All interactions details and references
2 total interaction(s) for 2 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1

Genetic Interactions
  • Synthetic Rescue: 1

Sequence Information
ChrVI:264191 to 265213 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2003-09-26 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1023 264191..265213 2003-09-26 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001952

IRC7 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for IRC7]

1) Alvaro D, et al.  (2007) Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet 3(12):e228
2) Hansen J and Johannesen PF  (2000) Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet 263(3):535-42
3) Gross C, et al.  (2000) Identification of the copper regulon in Saccharomyces cerevisiae by DNA microarrays. J Biol Chem 275(41):32310-6
4) Scherens B, et al.  (2006) Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term. FEMS Yeast Res 6(5):777-91