KEG1/YFR042W Summary Help

Standard Name KEG1 1
Systematic Name YFR042W
Feature Type ORF, Verified
Description Integral membrane protein of the ER; physically interacts with Kre6p; has a role in the synthesis of beta-1,6-glucan in the cell wall; required for cell viability (1, 2)
Name Description Kre6-binding ER protein responsible for Glucan synthesis 1
Chromosomal Location
ChrVI:238458 to 239060 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All KEG1 GO evidence and references
  View Computational GO annotations for KEG1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
overexpression
Resources
20 total interaction(s) for 14 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 5
  • Two-hybrid: 4

Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Suppression: 3
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 200
Molecular Weight (Da) 23,555
Isoelectric Point (pI) 10.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVI:238458 to 239060 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..603 238458..239060 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001938
References cited on this page View Complete Literature Guide for KEG1
1) Nakamata K, et al.  (2007) KEG1/YFR042w Encodes a Novel Kre6-binding Endoplasmic Reticulum Membrane Protein Responsible for beta-1,6-Glucan Synthesis in Saccharomyces cerevisiae. J Biol Chem 282(47):34315-24
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91