OSW7/YFR039C Summary Help

Standard Name OSW7 1
Systematic Name YFR039C
Feature Type ORF, Verified
Description Protein involved in outer spore wall assembly; likely involved directly in dityrosine layer assembly; may be involved in response to high salt and changes in carbon source; deletion mutant has decreased spore survival in Drosophila feces; OSW7 has a paralog, SHE10, that arose from the whole genome duplication; deletion of both OSW7 and SHE10 results in reduced dityrosine fluorescence from the spore wall relative to other mutants (1, 2, 3, 4, 5)
Name Description Outer Spore Wall 1
Chromosomal Location
ChrVI:233544 to 232012 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All OSW7 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Large-scale survey
null
overexpression
Resources
10 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Biochemical Activity: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 510
Molecular Weight (Da) 59,359
Isoelectric Point (pI) 4.5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVI:233544 to 232012 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1533 233544..232012 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001935
References cited on this page View Complete Literature Guide for OSW7
1) Lin CP, et al.  (2013) A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in S. cerevisiae. PLoS Genet 9(8):e1003700
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Musso G, et al.  (2008) The extensive and condition-dependent nature of epistasis among whole-genome duplicates in yeast. Genome Res 18(7):1092-9
5) Coluccio AE, et al.  (2008) The yeast spore wall enables spores to survive passage through the digestive tract of Drosophila. PLoS One 3(8):e2873