Standard Name	PTR3 1
Systematic Name	YFR029W
Alias	SSY3 2 , RAA2 3
Feature Type	ORF, Verified
Description	Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes (4, 5)
Name Description	Peptide TRansport 1

Chromosomal Location	ChrVI:210937 to 212973 | ORF Map | GBrowse
	Genetic position: 46 cM

	View Computational GO annotations for PTR3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	response to amino acid stimulus (IMP)
Cellular Component
Manually curated	extrinsic to plasma membrane (IDA)

Classical genetics
null	resistance to L-methionine: increased resistance to f-phenylalanine: increased resistance to ethionine: increased resistance to nikkomycin: increased resistance to L-azetidine-2-carboxylate: increased resistance to L-histidine: increased viable
Large-scale survey
null	inviable resistance to sulfanilamide: decreased resistance to ethanol: decreased
overexpression	cell cycle progression: abnormal
reduction of function	competitive fitness: increased resistance to methyl methanesulfonate: decreased resistance to sirolimus: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	82 total interaction(s) for 73 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-RNA: 1 Affinity Capture-Western: 2 Biochemical Activity: 3 Protein-RNA: 1 Two-hybrid: 6
Genetic Interactions	Dosage Rescue: 4 Negative Genetic: 44 Phenotypic Enhancement: 2 Phenotypic Suppression: 1 Positive Genetic: 1 Synthetic Lethality: 2 Synthetic Rescue: 12
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVI:210937 to 212973 | ORF Map | GBrowse
	Genetic position: 46 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2037 210937..212973 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001925