SAD1/YFR005C Summary Help

Standard Name SAD1 1 (see Nomenclature conflict Note)
Systematic Name YFR005C
Feature Type ORF, Verified
Description Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for assembly of U4 snRNA into the U4/U6 particle (1)
Name Description SnRNP Assembly Defective 1
Chromosomal Location
ChrVI:155873 to 154527 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SAD1 GO evidence and references
  View Computational GO annotations for SAD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Large-scale survey
conditional
null
reduction of function
Resources
11 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Co-purification: 1

Genetic Interactions
  • Phenotypic Enhancement: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVI:155873 to 154527 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1347 155873..154527 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001901

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
RAD53Nomenclature conflictSAD1 has been used to refer to both RAD53/YPL153C, a checkpoint protein involved in DNA repair, and SAD1/YFR005C, a protein involved in mRNA splicing.
References cited on this page View Complete Literature Guide for SAD1
1) Lygerou Z, et al.  (1999) A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing. Mol Cell Biol 19(3):2008-20