PXL1/YKR090W Summary

PXL1 BASIC INFORMATION

Standard Name	PXL1 1
Systematic Name	YKR090W
Feature Type	ORF, Verified
Description	LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin (1)
Name Description	PaXillin-Like protein 1

GO Annotations	All PXL1 GO evidence and references
	View Computational GO annotations for PXL1
Molecular Function
Manually curated	protein binding (ISS)
Biological Process
Manually curated	maintenance of cell polarity (IMP)
Cellular Component
Manually curated	cellular bud neck (IDA) cellular bud tip (IDA) incipient cellular bud site (IDA) mating projection tip (IDA)
High-throughput	cellular bud (IDA) cellular bud neck (IDA) cytoplasm (IDA)

Mutant Phenotype	All PXL1 Phenotype details and references
Large-scale survey
null	viable

Interactions	PXL1 All interactions details and references
	16 total interaction(s) for 15 unique genes/features.
Physical Interactions	Biochemical Activity: 10 Reconstituted Complex: 1 Two-hybrid: 1
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 1 Synthetic Growth Defect: 1 Synthetic Rescue: 1

Sequence Information

ChrXI:608588 to 610708 | |

Last Update

Coordinates: 2005-12-15 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2121	608588..610708	2005-12-15	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001798

PXL1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PXL1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PXL1]

1)	Mackin NA, et al. (2004) The PXL1 gene of Saccharomyces cerevisiae encodes a paxillin-like protein functioning in polarized cell growth. Mol Biol Cell 15(4):1904-17

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