MSA2/YKR077W Summary Help

Standard Name MSA2 1
Systematic Name YKR077W
Feature Type ORF, Verified
Description Putative transcriptional activator; interacts with G1-specific transcription factor MBF and G1-specific promoters; MSA2 has a paralog, MSA1, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Mbf and Sbf Associated 1
Chromosomal Location
ChrXI:583653 to 584744 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MSA2 GO evidence and references
  View Computational GO annotations for MSA2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 1 genes
Resources
Large-scale survey
null
overexpression
Resources
49 total interaction(s) for 39 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 4
  • Protein-RNA: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 4

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 30
  • Phenotypic Enhancement: 1
  • Positive Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 363
Molecular Weight (Da) 39,862
Isoelectric Point (pI) 10.89
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:583653 to 584744 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1092 583653..584744 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001785
References cited on this page View Complete Literature Guide for MSA2
1) Ashe M, et al.  (2008) The SBF- and MBF-associated Protein Msa1 Is Required for Proper Timing of G1-specific Transcription in Saccharomyces cerevisiae. J Biol Chem 283(10):6040-9
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Titz B, et al.  (2006) Transcriptional activators in yeast. Nucleic Acids Res 34(3):955-67