Standard Name	BET3
Systematic Name	YKR068C
Feature Type	ORF, Verified
Description	Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex (1, 2)
Name Description	Blocked Early in Transport 3

Chromosomal Location	ChrXI:570909 to 570328 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for BET3
Molecular Function
Manually curated	contributes_to Rab guanyl-nucleotide exchange factor activity (IDA, IGI, IMP)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IGI, IMP) intra-Golgi vesicle-mediated transport (IMP)
Cellular Component
Manually curated	cis-Golgi network membrane (IDA) TRAPP complex (IDA)

Classical genetics
conditional	endomembrane system morphology: abnormal endoplasmic reticulum morphology: abnormal invertase transport: decreased carboxypeptidase Y (CPY) transport: decreased
null	inviable
Large-scale survey
conditional	heat sensitivity: increased
null	inviable resistance to clioquinol: decreased
reduction of function	competitive fitness: decreased resistance to hydroxyurea: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	201 total interaction(s) for 76 unique genes/features.
Physical Interactions	Affinity Capture-MS: 47 Affinity Capture-RNA: 3 Affinity Capture-Western: 57 Biochemical Activity: 1 Co-crystal Structure: 1 Co-fractionation: 2 Co-purification: 6 Reconstituted Complex: 1 Two-hybrid: 16
Genetic Interactions	Dosage Lethality: 4 Dosage Rescue: 14 Negative Genetic: 26 Positive Genetic: 1 Synthetic Growth Defect: 2 Synthetic Lethality: 20
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXI:570909 to 570328 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..582 570909..570328 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001776